Which of the following is a symptom of acute toxicity?

Acute toxicity refers to the adverse effects that occur soon after exposure to a toxic substance, often within a short period and usually as a result of a single, high exposure. The correct symptom indicative of acute toxicity is the presence of blisters, which can result from the skin's reaction to certain toxic compounds. Blisters often form at the site of exposure, indicating that the skin is reacting chemically to a toxic agent, which is characteristic of acute toxicity scenarios.

While reduced body weight, tremors, and skin irritation can indeed be related to various toxicological effects, they do not specifically pinpoint acute toxicity in the same way that blisters do. Reduced body weight takes longer to manifest and usually indicates prolonged exposure or chronic effects. Tremors may suggest neurological involvement but are not as directly associated with acute chemical burns or irritations as blisters. Skin irritation can occur from many irritants that do not necessarily qualify as acute toxic effects. Hence, blisters serve as a clear, immediate indicator of acute toxicity.